Random Research highlight: 3D Brownian motion simulator: A wide variety of nanobiotechnologic applications are being developed for nanoparticle based in vitro diagnostic and imaging systems. Some of these systems make possible highly sensitive detection of molecular biomarkers. Frequently, the very low concentration of the biomarkers makes impossible the classical, partial differential equation-based mathematical simulation of the motion of the nanoparticles involved. We present a three-dimensional Brownian motion simulation webserver for the prediction of the movement of nanoparticles in various thermal, viscosity, and geometric settings in a rectangular cuvette. IEEE Transactions on Nanobioscience, Vol. 10, No. 4, pp. 248-249; December 2011.